CODEINE NO FURTHER A MYSTERY

Grapefruit Juice (GFJ)- I had toyed with the thought of utilizing grapefruit juice for many years but have examine combined reports. Recently I go through that it does not inhibit CYP2D6 but rahter 3A4 that's responsible for conversion of codeine into norcodeine. In theory by inhibiting 3A4 you leave much more codeine for 2D6 to change into morphin